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Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using the Neisseria gonorrhoeae ribonucleotide reductase inactive complex
Ribonucleotide reductase (RNR) is an essential enzyme that converts ribonucleotides to deoxyribonucleotides and is a promising antibiotic target, but few RNRs have been structurally characterized. We present the use of the chameleon, a commercially-available piezoelectric cryogenic electron microsco...
Autores principales: | Levitz, Talya S., Brignole, Edward J., Fong, Ivan, Darrow, Michele C., Drennan, Catherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994553/ https://www.ncbi.nlm.nih.gov/pubmed/34906669 http://dx.doi.org/10.1016/j.jsb.2021.107825 |
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