Ibandronate promotes autophagy by inhibiting Rac1–mTOR signaling pathway in vitro and in vivo

We previously reported that ibandronate (IBAN) could improve endothelial function in spontaneously hypertensive rats. However, the mechanism by which IBAN improves endothelial function is unclear. The IBAN-induced autophagic process in vitro experiments were determined by detection of LC3, Beclin1,...

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Detalles Bibliográficos
Autores principales: Han, Jie, Yang, Jian, Wang, Qiqi, Yin, Xiang, Sun, Zewei, Huang, Chaoyang, Chen, Guoping, Zheng, Liangrong, Jiang, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994753/
https://www.ncbi.nlm.nih.gov/pubmed/35397636
http://dx.doi.org/10.1038/s41420-022-00995-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994753/
https://www.ncbi.nlm.nih.gov/pubmed/35397636
http://dx.doi.org/10.1038/s41420-022-00995-6

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