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N6-methyladenosine demethylase FTO suppressed prostate cancer progression by maintaining CLIC4 mRNA stability

The fat mass and obesity-associated protein (FTO) is an N6-Methyladenosine (m6A) demethylase, which has been revealed to play critical roles in tumorigenesis. However, its role in the development and progression of prostate cancer (PCa) remains poorly understood. Here, we aimed to investigate the fu...

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Detalles Bibliográficos
Autores principales: Zou, Libin, Chen, Wenbin, Zhou, Xumin, Yang, Taowei, Luo, Junqi, Long, Zining, Wu, Jun, Lv, Daojun, Mao, Xiangming, Cen, Shengren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994758/
https://www.ncbi.nlm.nih.gov/pubmed/35397614
http://dx.doi.org/10.1038/s41420-022-01003-7