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Phenanthrene-enriched extract from Eulophia macrobulbon using subcritical dimethyl ether for phosphodiesterase-5A1 inhibition

Eulophia macrobulbon (E.C.Parish & Rchb.f.) Hook.f. contains a natural PDE5A1 inhibitor, phenanthrene, 1-(4'-hydroxybenzyl)-4,8- dimethoxyphenanthrene-2,7-diol (HDP), a potential agent for the treatment of erectile dysfunction. The aim of this study was to improve the extraction efficiency...

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Detalles Bibliográficos
Autores principales: Srivilai, Jukkarin, Boonnoun, Panatpong, Saesong, Tongchai, Pingyod, Chitaporn, Chaichamnong, Nattiya, Engsuwan, Jinutda, Temkitthawon, Prapapan, Scholfield, C. Norman, Nuengchamnong, Nitra, Khorana, Nantaka, Ingkaninan, Kornkanok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994770/
https://www.ncbi.nlm.nih.gov/pubmed/35397625
http://dx.doi.org/10.1038/s41598-022-08553-x