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Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells

The mean survival of metastatic melanoma is less than 1 year. While the high mortality rate is associated with the efficient metastatic colonization of the involved organs, the underlying mechanisms remain elusive. The role of exosomes in facilitating the interactions between cancer cells and the me...

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Detalles Bibliográficos
Autores principales: Zhao, Qiting, Chen, Hao, Li, Xiaoshuang, Zeng, Bin, Sun, Zhiwei, Liu, Doudou, Chen, Yuting, Zhang, Yuhan, Rosie Xing, H., Wang, Jianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994777/
https://www.ncbi.nlm.nih.gov/pubmed/35397647
http://dx.doi.org/10.1038/s41420-022-00993-8