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A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis
The transient receptor potential melastatin 4 (TRPM4) channel contributes to disease severity in the murine experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis and to neuronal cell death in models of excitotoxicity and traumatic brain injury. As TRPM4 is activated by intracel...
Autores principales: | Fearey, Brenna C., Binkle, Lars, Mensching, Daniel, Schulze, Christian, Lohr, Christian, Friese, Manuel A., Oertner, Thomas G., Gee, Christine E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994783/ https://www.ncbi.nlm.nih.gov/pubmed/35397639 http://dx.doi.org/10.1038/s41598-022-09875-6 |
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