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Efficacy of Spironolactone as an Adjunctive Therapy to Risperidone to Improve Symptoms of Schizophrenia: A Double-Blind, Randomized, Placebo-Controlled, Clinical Trial

Objective: Spironolactone (C24H32O4S), a potent mineralocorticoid receptor (MR) inhibitor, is a potassium-sparing diuretic that is traditionally used to treat fluid build-up in the body or for its anti-androgenic properties. This study is a double-blind, placebo-controlled, randomized clinical trial...

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Detalles Bibliográficos
Autores principales: Zandifar, Atefeh, Badrfam, Rahim, Sanjari Moghaddam, Hossein, Akhondzadeh, Shahin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994842/
https://www.ncbi.nlm.nih.gov/pubmed/35480128
http://dx.doi.org/10.18502/ijps.v17i1.8045