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Inhibiting nuclear factor erythroid 2 related factor 2-mediated autophagy in bovine mammary epithelial cells induces oxidative stress in response to exogenous fatty acids

BACKGROUND: In early lactation, bovine mammary epithelial cells undergo serious metabolic challenges and oxidative stress both of which could be alleviated by activation of autophagy. Nuclear factor erythroid 2 related factor 2 (NFE2L2), a master regulator of cellular redox homeostasis, plays an imp...

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Detalles Bibliográficos
Autores principales: Chang, Renxu, Sun, Xudong, Jia, Hongdou, Xu, Qiushi, Dong, Zhihao, Tang, Yan, Luo, Shengbin, Jiang, Qianming, Loor, Juan J., Xu, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994900/
https://www.ncbi.nlm.nih.gov/pubmed/35397612
http://dx.doi.org/10.1186/s40104-022-00695-2