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Incentives, lockdown, and testing: from Thucydides’ analysis to the COVID-19 pandemic

In this work, we provide a general mathematical formalism to study the optimal control of an epidemic, such as the COVID-19 pandemic, via incentives to lockdown and testing. In particular, we model the interplay between the government and the population as a principal–agent problem with moral hazard...

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Autores principales: Hubert, Emma, Mastrolia, Thibaut, Possamaï, Dylan, Warin, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995008/
https://www.ncbi.nlm.nih.gov/pubmed/35397720
http://dx.doi.org/10.1007/s00285-022-01736-0
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author Hubert, Emma
Mastrolia, Thibaut
Possamaï, Dylan
Warin, Xavier
author_facet Hubert, Emma
Mastrolia, Thibaut
Possamaï, Dylan
Warin, Xavier
author_sort Hubert, Emma
collection PubMed
description In this work, we provide a general mathematical formalism to study the optimal control of an epidemic, such as the COVID-19 pandemic, via incentives to lockdown and testing. In particular, we model the interplay between the government and the population as a principal–agent problem with moral hazard, à la Cvitanić et al. (Finance Stoch 22(1):1–37, 2018), while an epidemic is spreading according to dynamics given by compartmental stochastic SIS or SIR models, as proposed respectively by Gray et al. (SIAM J Appl Math 71(3):876–902, 2011) and Tornatore et al. (Phys A Stat Mech Appl 354(15):111–126, 2005). More precisely, to limit the spread of a virus, the population can decrease the transmission rate of the disease by reducing interactions between individuals. However, this effort—which cannot be perfectly monitored by the government—comes at social and monetary cost for the population. To mitigate this cost, and thus encourage the lockdown of the population, the government can put in place an incentive policy, in the form of a tax or subsidy. In addition, the government may also implement a testing policy in order to know more precisely the spread of the epidemic within the country, and to isolate infected individuals. In terms of technical results, we demonstrate the optimal form of the tax, indexed on the proportion of infected individuals, as well as the optimal effort of the population, namely the transmission rate chosen in response to this tax. The government’s optimisation problems then boils down to solving an Hamilton–Jacobi–Bellman equation. Numerical results confirm that if a tax policy is implemented, the population is encouraged to significantly reduce its interactions. If the government also adjusts its testing policy, less effort is required on the population side, individuals can interact almost as usual, and the epidemic is largely contained by the targeted isolation of positively-tested individuals.
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spelling pubmed-89950082022-04-11 Incentives, lockdown, and testing: from Thucydides’ analysis to the COVID-19 pandemic Hubert, Emma Mastrolia, Thibaut Possamaï, Dylan Warin, Xavier J Math Biol Article In this work, we provide a general mathematical formalism to study the optimal control of an epidemic, such as the COVID-19 pandemic, via incentives to lockdown and testing. In particular, we model the interplay between the government and the population as a principal–agent problem with moral hazard, à la Cvitanić et al. (Finance Stoch 22(1):1–37, 2018), while an epidemic is spreading according to dynamics given by compartmental stochastic SIS or SIR models, as proposed respectively by Gray et al. (SIAM J Appl Math 71(3):876–902, 2011) and Tornatore et al. (Phys A Stat Mech Appl 354(15):111–126, 2005). More precisely, to limit the spread of a virus, the population can decrease the transmission rate of the disease by reducing interactions between individuals. However, this effort—which cannot be perfectly monitored by the government—comes at social and monetary cost for the population. To mitigate this cost, and thus encourage the lockdown of the population, the government can put in place an incentive policy, in the form of a tax or subsidy. In addition, the government may also implement a testing policy in order to know more precisely the spread of the epidemic within the country, and to isolate infected individuals. In terms of technical results, we demonstrate the optimal form of the tax, indexed on the proportion of infected individuals, as well as the optimal effort of the population, namely the transmission rate chosen in response to this tax. The government’s optimisation problems then boils down to solving an Hamilton–Jacobi–Bellman equation. Numerical results confirm that if a tax policy is implemented, the population is encouraged to significantly reduce its interactions. If the government also adjusts its testing policy, less effort is required on the population side, individuals can interact almost as usual, and the epidemic is largely contained by the targeted isolation of positively-tested individuals. Springer Berlin Heidelberg 2022-04-10 2022 /pmc/articles/PMC8995008/ /pubmed/35397720 http://dx.doi.org/10.1007/s00285-022-01736-0 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Hubert, Emma
Mastrolia, Thibaut
Possamaï, Dylan
Warin, Xavier
Incentives, lockdown, and testing: from Thucydides’ analysis to the COVID-19 pandemic
title Incentives, lockdown, and testing: from Thucydides’ analysis to the COVID-19 pandemic
title_full Incentives, lockdown, and testing: from Thucydides’ analysis to the COVID-19 pandemic
title_fullStr Incentives, lockdown, and testing: from Thucydides’ analysis to the COVID-19 pandemic
title_full_unstemmed Incentives, lockdown, and testing: from Thucydides’ analysis to the COVID-19 pandemic
title_short Incentives, lockdown, and testing: from Thucydides’ analysis to the COVID-19 pandemic
title_sort incentives, lockdown, and testing: from thucydides’ analysis to the covid-19 pandemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995008/
https://www.ncbi.nlm.nih.gov/pubmed/35397720
http://dx.doi.org/10.1007/s00285-022-01736-0
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