Cargando…

Phosphorylation of Spastin Promotes the Surface Delivery and Synaptic Function of AMPA Receptors

Synaptic plasticity is essential for cognitive functions such as learning and memory. One of the mechanisms involved in synaptic plasticity is the dynamic delivery of AMPA receptors (AMPARs) in and out of synapses. Mutations of SPAST, which encodes SPASTIN, a microtubule-severing protein, are consid...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Li, Wang, Hanjie, Cha, Shuhan, Li, Jiong, Zhang, Jiaqi, Wu, Jiaming, Guo, Guoqing, Zhang, Jifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995424/
https://www.ncbi.nlm.nih.gov/pubmed/35418834
http://dx.doi.org/10.3389/fncel.2022.809934