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Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque

The accurate germline gene assignment and assessment of somatic hypermutation in antibodies induced by immunization or infection are important in immunological studies. Here, we illustrate issues specific to the construction of comprehensive immunoglobulin (IG) germline gene reference databases for...

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Detalles Bibliográficos
Autores principales: Kaduk, Mateusz, Corcoran, Martin, Karlsson Hedestam, Gunilla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995469/
https://www.ncbi.nlm.nih.gov/pubmed/35419009
http://dx.doi.org/10.3389/fimmu.2022.818440