Increased Ascorbate Content of Glioblastoma Is Associated With a Suppressed Hypoxic Response and Improved Patient Survival

Glioblastoma multiforme is a challenging disease with limited treatment options and poor survival. Glioblastoma tumours are characterised by hypoxia that activates the hypoxia inducible factor (HIF) pathway and controls a myriad of genes that drive cancer progression. HIF transcription factors are r...

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Detalles Bibliográficos
Autores principales: Burgess, Eleanor R., Crake, Rebekah L. I., Phillips, Elisabeth, Morrin, Helen R., Royds, Janice A., Slatter, Tania L., Wiggins, George A. R., Vissers, Margreet C. M., Robinson, Bridget A., Dachs, Gabi U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995498/
https://www.ncbi.nlm.nih.gov/pubmed/35419292
http://dx.doi.org/10.3389/fonc.2022.829524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995498/
https://www.ncbi.nlm.nih.gov/pubmed/35419292
http://dx.doi.org/10.3389/fonc.2022.829524

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