Mice Dually Disrupted for Nod2 and Mincle Manifest Early Bacteriological Control but Late Susceptibility During Mycobacterium tuberculosis Infection

Pattern recognition receptors Mincle and NOD2 have been implicated in mycobacterial immunity. However, knockout (KO) animal infection studies with Mycobacterium tuberculosis (Mtb) have had mild/delayed phenotypes. Given that genetic susceptibility to infectious diseases can be polygenic, we hypothes...

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Detalles Bibliográficos
Autores principales: Dubé, Jean-Yves, McIntosh, Fiona, Behr, Marcel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995500/
https://www.ncbi.nlm.nih.gov/pubmed/35418999
http://dx.doi.org/10.3389/fimmu.2022.862992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995500/
https://www.ncbi.nlm.nih.gov/pubmed/35418999
http://dx.doi.org/10.3389/fimmu.2022.862992

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