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Serum autotaxin levels in chronic disease and acute exacerbation of fibrosing interstitial lung disease

BACKGROUND: Autotaxin (ATX) is an ecto-enzyme that catalyses the hydrolysis of lysophospholipids to the lipid mediator lysophosphatidic acid (LPA). LPA/ATX signalling has emerged as a new therapeutic target for pulmonary fibrosis; however, the serum levels and dynamics of ATX during the clinical cou...

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Detalles Bibliográficos
Autores principales: Isshiki, Takuma, Shimizu, Hiroshige, Sakamoto, Susumu, Yamasaki, Akira, Miyoshi, Shion, Nakamura, Yasuhiko, Homma, Sakae, Kishi, Kazuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995540/
https://www.ncbi.nlm.nih.gov/pubmed/35415191
http://dx.doi.org/10.1183/23120541.00683-2021