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Serum autotaxin levels in chronic disease and acute exacerbation of fibrosing interstitial lung disease
BACKGROUND: Autotaxin (ATX) is an ecto-enzyme that catalyses the hydrolysis of lysophospholipids to the lipid mediator lysophosphatidic acid (LPA). LPA/ATX signalling has emerged as a new therapeutic target for pulmonary fibrosis; however, the serum levels and dynamics of ATX during the clinical cou...
Autores principales: | Isshiki, Takuma, Shimizu, Hiroshige, Sakamoto, Susumu, Yamasaki, Akira, Miyoshi, Shion, Nakamura, Yasuhiko, Homma, Sakae, Kishi, Kazuma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995540/ https://www.ncbi.nlm.nih.gov/pubmed/35415191 http://dx.doi.org/10.1183/23120541.00683-2021 |
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