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Pharmacological modulation of prostaglandin E(2) (PGE(2)) EP receptors improves cardiomyocyte function under hyperglycemic conditions

Type 2 diabetes (T2D) affects >30 million Americans and nearly 70% of individuals with T2D will die from cardiovascular disease (CVD). Circulating levels of the inflammatory signaling lipid, prostaglandin E(2) (PGE(2)), are elevated in the setting of obesity and T2D and are associated with decrea...

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Detalles Bibliográficos
Autores principales: Bosma, Karin J., Ghosh, Monica, Andrei, Spencer R., Zhong, Lin, Dunn, Jennifer C., Ricciardi, Valerie F., Burkett, Juliann B., Hatzopoulos, Antonis K., Damron, Derek S., Gannon, Maureen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995713/
https://www.ncbi.nlm.nih.gov/pubmed/35403369
http://dx.doi.org/10.14814/phy2.15212