Decoy bypass for appetite suppression in obese adults: role of synergistic nutrient sensing receptors GPR84 and FFAR4 on colonic endocrine cells

OBJECTIVE: Colonic enteroendocrine cells (EECs) store and release potent anorectic hormones that are key regulators of satiety. EECs express multiple nutrient sensing receptors, particularly for medium-chain fatty acids (MCFAs): GPR84 and FFAR4. Here we show a non-surgical approach with targeted col...

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Detalles Bibliográficos
Autores principales: Peiris, Madusha, Aktar, Rubina, Reed, David, Cibert-Goton, Vincent, Zdanaviciene, Ausra, Halder, Writaja, Robinow, Adam, Corke, Simon, Dogra, Harween, Knowles, Charles H, Blackshaw, Ashley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Neurogastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995825/
https://www.ncbi.nlm.nih.gov/pubmed/34083384
http://dx.doi.org/10.1136/gutjnl-2020-323219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995825/
https://www.ncbi.nlm.nih.gov/pubmed/34083384
http://dx.doi.org/10.1136/gutjnl-2020-323219

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