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Decoy bypass for appetite suppression in obese adults: role of synergistic nutrient sensing receptors GPR84 and FFAR4 on colonic endocrine cells

OBJECTIVE: Colonic enteroendocrine cells (EECs) store and release potent anorectic hormones that are key regulators of satiety. EECs express multiple nutrient sensing receptors, particularly for medium-chain fatty acids (MCFAs): GPR84 and FFAR4. Here we show a non-surgical approach with targeted col...

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Detalles Bibliográficos
Autores principales:	Peiris, Madusha, Aktar, Rubina, Reed, David, Cibert-Goton, Vincent, Zdanaviciene, Ausra, Halder, Writaja, Robinow, Adam, Corke, Simon, Dogra, Harween, Knowles, Charles H, Blackshaw, Ashley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Neurogastroenterology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995825/ https://www.ncbi.nlm.nih.gov/pubmed/34083384 http://dx.doi.org/10.1136/gutjnl-2020-323219

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