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Efficacy of Tricaine (MS-222) and Hypothermia as Anesthetic Agents for Blocking Sensorimotor Responses in Larval Zebrafish

Tricaine, or MS-222, is the most commonly used chemical anesthetic in zebrafish research. It is thought to act via blocking voltage-gated sodium channels, though its mechanism of action, particularly at the neuronal level, is not yet fully understood. Here, we first characterized the effects of tric...

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Detalles Bibliográficos
Autores principales: Leyden, Claire, Brüggemann, Timo, Debinski, Florentyna, Simacek, Clara A., Dehmelt, Florian A., Arrenberg, Aristides B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996001/
https://www.ncbi.nlm.nih.gov/pubmed/35419446
http://dx.doi.org/10.3389/fvets.2022.864573