Ag120-Mediated Inhibition of ASCT2-Dependent Glutamine Transport has an Anti-Tumor Effect on Colorectal Cancer Cells

Metabolic reprogramming is considered to be a hallmark of cancer, and increased glutamine metabolism plays an important role in the progression of many tumors, including colorectal cancer (CRC). Targeting of glutamine uptake via the transporter protein ASCT2/SLC1A5 (solute carrier family 1 member 5)...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Huang, Jianwen, Dong, Qichao, Li, Wenting, Jiang, Lei, Zhang, Qian, Sun, Li, Yuan, Shengtao, He, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996072/
https://www.ncbi.nlm.nih.gov/pubmed/35418865
http://dx.doi.org/10.3389/fphar.2022.871392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996072/
https://www.ncbi.nlm.nih.gov/pubmed/35418865
http://dx.doi.org/10.3389/fphar.2022.871392

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