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Ag120-Mediated Inhibition of ASCT2-Dependent Glutamine Transport has an Anti-Tumor Effect on Colorectal Cancer Cells
Metabolic reprogramming is considered to be a hallmark of cancer, and increased glutamine metabolism plays an important role in the progression of many tumors, including colorectal cancer (CRC). Targeting of glutamine uptake via the transporter protein ASCT2/SLC1A5 (solute carrier family 1 member 5)...
Autores principales: | Yu, Wei, Huang, Jianwen, Dong, Qichao, Li, Wenting, Jiang, Lei, Zhang, Qian, Sun, Li, Yuan, Shengtao, He, Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996072/ https://www.ncbi.nlm.nih.gov/pubmed/35418865 http://dx.doi.org/10.3389/fphar.2022.871392 |
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