ASPP2 Coordinates ERS-Mediated Autophagy and Apoptosis Through mTORC1 Pathway in Hepatocyte Injury Induced by TNF-α

Background: Though ASPP2 plays an important role in regulating cell apoptosis and autophagy in case of liver injury, there remains a lack of clarity on the molecular mechanism of ASPP2 regulating autophagy and apoptosis. Methods: A hepatocyte injury model was constructed using HL7702 cell line and T...

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Detalles Bibliográficos
Autores principales: Yao, Jia, Yang, Hui, Wang, Han, Shi, Honglin, Jiao, Yan, Zhang, Ying, Chen, Dexi, Shi, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996113/
https://www.ncbi.nlm.nih.gov/pubmed/35418864
http://dx.doi.org/10.3389/fphar.2022.865389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996113/
https://www.ncbi.nlm.nih.gov/pubmed/35418864
http://dx.doi.org/10.3389/fphar.2022.865389

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