Ficolin-2 Lectin Complement Pathway Mediates Capsule-Specific Innate Immunity Against Invasive Pneumococcal Disease

Reports conflict regarding which lectin-microbial ligand interactions elicit a protective response from the lectin pathway (LP) of complement. Using fluorescent microscopy, we demonstrate the human lectin ficolin-2 binds to Streptococcus pneumoniae serotype 11A capsule polysaccharide dependent on th...

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Detalles Bibliográficos
Autores principales: Nahm, Moon H., Yu, Jigui, Calix, Juan J., Ganaie, Feroze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996173/
https://www.ncbi.nlm.nih.gov/pubmed/35418983
http://dx.doi.org/10.3389/fimmu.2022.841062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996173/
https://www.ncbi.nlm.nih.gov/pubmed/35418983
http://dx.doi.org/10.3389/fimmu.2022.841062

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