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Efficiently generate functional hepatic cells from human pluripotent stem cells by complete small-molecule strategy

BACKGROUND: Various methods have been developed to generate hepatic cells from human pluripotent stem cells (hPSCs) that rely on the combined use of multiple expensive growth factors, limiting industrial-scale production and widespread applications. Small molecules offer an attractive alternative to...

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Detalles Bibliográficos
Autores principales: Pan, Tingcai, Wang, Ning, Zhang, Jiaye, Yang, Fan, Chen, Yan, Zhuang, Yuanqi, Xu, Yingying, Fang, Ji, You, Kai, Lin, Xianhua, Li, Yang, Li, Shao, Liang, Kangyan, Li, Yin-xiong, Gao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996222/
https://www.ncbi.nlm.nih.gov/pubmed/35410439
http://dx.doi.org/10.1186/s13287-022-02831-1