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Cell models for Down syndrome-Alzheimer’s disease research

Down syndrome (DS) is the most common chromosomal abnormality and leads to intellectual disability, increased risk of cardiac defects, and an altered immune response. Individuals with DS have an extra full or partial copy of chromosome 21 (trisomy 21) and are more likely to develop early-onset Alzhe...

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Detalles Bibliográficos
Autores principales: Wu, Yixing, West, Nicole R., Bhattacharyya, Anita, Wiseman, Frances K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996251/
https://www.ncbi.nlm.nih.gov/pubmed/35449591
http://dx.doi.org/10.1042/NS20210054