Mutation rate of SARS-CoV-2 and emergence of mutators during experimental evolution

BACKGROUND AND OBJECTIVES: To understand how organisms evolve, it is fundamental to study how mutations emerge and establish. Here, we estimated the rate of mutation accumulation of SARS-CoV-2 in vitro and investigated the repeatability of its evolution when facing a new cell type but no immune or d...

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Detalles Bibliográficos
Autores principales: Amicone, Massimo, Borges, Vítor, Alves, Maria João, Isidro, Joana, Zé-Zé, Líbia, Duarte, Sílvia, Vieira, Luís, Guiomar, Raquel, Gomes, João Paulo, Gordo, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996265/
https://www.ncbi.nlm.nih.gov/pubmed/35419205
http://dx.doi.org/10.1093/emph/eoac010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996265/
https://www.ncbi.nlm.nih.gov/pubmed/35419205
http://dx.doi.org/10.1093/emph/eoac010

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