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Identification of 1, 2, 4-Triazine and Its Derivatives Against Lanosterol 14-Demethylase (CYP51) Property of Candida albicans: Influence on the Development of New Antifungal Therapeutic Strategies

This research aims to find out whether the 1, 2, 4-triazine and its derivatives have antifungal effects and can protect humans from infection with Candida albicans. Molecular docking and molecular dynamic simulation are widely used in modern drug design to target a particular protein with a ligand....

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Detalles Bibliográficos
Autores principales: Verma, Abhishek Kumar, Majid, Aarfah, Hossain, Md. Shahadat, Ahmed, SK. Faisal, Ashid, Mohammad, Bhojiya, Ali Asger, Upadhyay, Sudhir K., Vishvakarma, Naveen Kumar, Alam, Mudassir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996309/
https://www.ncbi.nlm.nih.gov/pubmed/35419560
http://dx.doi.org/10.3389/fmedt.2022.845322