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Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage

BACKGROUND: Interactions of chromatin with the nuclear lamina via lamina-associated domains (LADs) confer structural stability to the genome. The dynamics of positioning of LADs during differentiation, and how LADs impinge on developmental gene expression, remains, however, elusive. RESULTS: We exam...

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Detalles Bibliográficos
Autores principales: Madsen-Østerbye, Julia, Abdelhalim, Mohamed, Baudement, Marie-Odile, Collas, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996409/
https://www.ncbi.nlm.nih.gov/pubmed/35410387
http://dx.doi.org/10.1186/s13059-022-02662-6