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Comparative bioavailability study following a single dose intravenous and buccal administration of remdesivir in rabbits
As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration, there is an urgent need of effective oral antiviral formulations to be used at early stage of infection in an outpatient setting. The present paper repor...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996499/ https://www.ncbi.nlm.nih.gov/pubmed/35421532 http://dx.doi.org/10.1016/j.ijpharm.2022.121739 |