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Comparative bioavailability study following a single dose intravenous and buccal administration of remdesivir in rabbits

As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration, there is an urgent need of effective oral antiviral formulations to be used at early stage of infection in an outpatient setting. The present paper repor...

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Detalles Bibliográficos
Autores principales: Szente, Lajos, Renkecz, Tibor, Sirok, Dávid, Stáhl, János, Hirka, Gábor, Puskás, István, Sohajda, Tamás, Fenyvesi, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996499/
https://www.ncbi.nlm.nih.gov/pubmed/35421532
http://dx.doi.org/10.1016/j.ijpharm.2022.121739