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Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression

BACKGROUND: Extracellular vesicles (EVs) are emerging mediators of intercellular communication that have been shown to play important roles in tumor progression. YRNA fragments, a type of small non-coding RNA, are dysregulated in non-small cell lung cancer (NSCLC) cell-derived EVs, suggesting that t...

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Detalles Bibliográficos
Autores principales: Li, Chuang, Wang, Wei, Sun, Yuting, Ni, Yifan, Qin, Fang, Li, Xiaolu, Wang, Tao, Guo, Mingxiong, Sun, Guihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996536/
https://www.ncbi.nlm.nih.gov/pubmed/35410432
http://dx.doi.org/10.1186/s13046-022-02346-w