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Chemically defined and small molecules-based generation of sinoatrial node-like cells

BACKGROUND: Existing methods for in vitro differentiation of human pluripotent stem cells (hPSCs) into sinoatrial node-like cells (SANLCs) require complex and undefined medium constituents. This might hinder the elucidation of the molecular mechanisms involved in cardiac subtype specification and pr...

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Detalles Bibliográficos
Autores principales: Hou, Xiaojie, Ma, Shuhong, Fan, Wei, Li, Fang, Xu, Miaomiao, Yang, Chao, Liu, Feng, Yan, Ying, Wan, Juyi, Lan, Feng, Liao, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996538/
https://www.ncbi.nlm.nih.gov/pubmed/35410454
http://dx.doi.org/10.1186/s13287-022-02834-y