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Mitigated suppressive function of regulatory T cells (Treg) upon Th17-inducing cytokines in oligo- and polyarticular Juvenile Idiopathic Arthritis (JIA) patients

BACKGROUND: The plasticity of T helper-17 (Th17) and regulatory T (Treg) cells may be a clue to pathogenesis of Juvenile Idiopathic Arthritis (JIA). It is still unclear, whether targeted suppression of Interleukin (IL)-17 is able to influence regulatory function of Treg to control pro-inflammatory e...

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Detalles Bibliográficos
Autores principales: Holzer, Marie-Therese, Almanzar, Giovanni, Woidich, Robert, Hügle, Boris, Haas, Johannes-Peter, Prelog, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996624/
https://www.ncbi.nlm.nih.gov/pubmed/35410224
http://dx.doi.org/10.1186/s12969-022-00680-z