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Mitigated suppressive function of regulatory T cells (Treg) upon Th17-inducing cytokines in oligo- and polyarticular Juvenile Idiopathic Arthritis (JIA) patients

BACKGROUND: The plasticity of T helper-17 (Th17) and regulatory T (Treg) cells may be a clue to pathogenesis of Juvenile Idiopathic Arthritis (JIA). It is still unclear, whether targeted suppression of Interleukin (IL)-17 is able to influence regulatory function of Treg to control pro-inflammatory e...

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Detalles Bibliográficos
Autores principales:	Holzer, Marie-Therese, Almanzar, Giovanni, Woidich, Robert, Hügle, Boris, Haas, Johannes-Peter, Prelog, Martina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996624/ https://www.ncbi.nlm.nih.gov/pubmed/35410224 http://dx.doi.org/10.1186/s12969-022-00680-z

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