Transcriptome analysis reveals key genes modulated by ALK5 inhibition in a bleomycin model of systemic sclerosis

OBJECTIVE: SSc is a rheumatic autoimmune disease affecting roughly 20 000 people worldwide and characterized by excessive collagen accumulation in the skin and internal organs. Despite the high morbidity and mortality associated with SSc, there are no approved disease-modifying agents. Our objective...

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Detalles Bibliográficos
Autores principales: Decato, Benjamin E, Ammar, Ron, Reinke-Breen, Lauren, Thompson, John R, Azzara, Anthony V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996787/
https://www.ncbi.nlm.nih.gov/pubmed/34289031
http://dx.doi.org/10.1093/rheumatology/keab580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996787/
https://www.ncbi.nlm.nih.gov/pubmed/34289031
http://dx.doi.org/10.1093/rheumatology/keab580

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