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Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis

OBJECTIVES: Advances in immunotherapy by blocking TNF have remarkably improved treatment outcomes for Rheumatoid arthritis (RA) patients. Although treatment specifically targets TNF, the downstream mechanisms of immune suppression are not completely understood. The aim of this study was to detect bi...

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Detalles Bibliográficos
Autores principales: Yoosuf, Niyaz, Maciejewski, Mateusz, Ziemek, Daniel, Jelinsky, Scott A, Folkersen, Lasse, Müller, Malin, Sahlström, Peter, Vivar, Nancy, Catrina, Anca, Berg, Louise, Klareskog, Lars, Padyukov, Leonid, Brynedal, Boel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996791/
https://www.ncbi.nlm.nih.gov/pubmed/34175943
http://dx.doi.org/10.1093/rheumatology/keab521