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Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

SIMPLE SUMMARY: Despite the successful introduction of targeted therapies, Chronic Lymphocytic Leukemia (CLL) remains incurable. This is thought to be partially due to the pro-survival and anti-apoptotic signaling that CLL cells receive from the lymph node microenvironment. Therefore, inhibition of...

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Detalles Bibliográficos
Autores principales: Burley, Thomas A., Hesketh, Andrew, Bucca, Giselda, Kennedy, Emma, Ladikou, Eleni E., Towler, Benjamin P., Mitchell, Simon, Smith, Colin P., Fegan, Christopher, Johnston, Rosalynd, Pepper, Andrea, Pepper, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996841/
https://www.ncbi.nlm.nih.gov/pubmed/35406371
http://dx.doi.org/10.3390/cancers14071600