Cargando…
Regulation of Let-7a-5p and miR-199a-5p Expression by Akt1 Modulates Prostate Cancer Epithelial-to-Mesenchymal Transition via the Transforming Growth Factor-β Pathway
SIMPLE SUMMARY: The molecular mechanisms regulating the switch from the growth of tumor cells to invasive phenotype for metastasis is largely unknown. Molecules such as Akt1 and TGFβ have been demonstrated to play reciprocal roles in the early and advanced stages of cancers, and epithelial-to-mesenc...
Autores principales: | Alwhaibi, Abdulrahman, Parvathagiri, Varun, Verma, Arti, Artham, Sandeep, Adil, Mir S., Somanath, Payaningal R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996869/ https://www.ncbi.nlm.nih.gov/pubmed/35406397 http://dx.doi.org/10.3390/cancers14071625 |
Ejemplares similares
-
Endothelial Akt1 loss promotes prostate cancer metastasis via β-catenin-regulated tight-junction protein turnover
por: Gao, Fei, et al.
Publicado: (2018) -
Claudin-17 Deficiency in Mice Results in Kidney Injury Due to Electrolyte Imbalance and Oxidative Stress
por: Adil, Mir S., et al.
Publicado: (2022) -
Modulation in the microRNA repertoire is responsible for the stage-specific effects of Akt suppression on murine neuroendocrine prostate cancer
por: Alwhaibi, Abdulrahman, et al.
Publicado: (2018) -
Genome atlas analysis based profiling of Akt pathway genes in the early and advanced human prostate cancer
por: Alwhaibi, Abdulrahman, et al.
Publicado: (2019) -
Sterically stabilized liposomes targeting P21 (RAC1) activated kinase-1 and secreted phospholipase A(2) suppress prostate cancer growth and metastasis
por: Verma, Arti, et al.
Publicado: (2020)