Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling

SIMPLE SUMMARY: The recent discovery of the genetic identity of the tubulin carboxypeptidase (TCP) provides a unique opportunity to study the role of the detyrosination of α-tubulin (deTyr-Tub), as performed by the TCP, in breast epithelial cells and breast cancer cells. Previous research has shown...

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Detalles Bibliográficos
Autores principales: Mathias, Trevor J., Ju, Julia A., Lee, Rachel M., Thompson, Keyata N., Mull, Makenzy L., Annis, David A., Chang, Katarina T., Ory, Eleanor C., Stemberger, Megan B., Hotta, Takashi, Ohi, Ryoma, Vitolo, Michele I., Moutin, Marie-Jo, Martin, Stuart S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996877/
https://www.ncbi.nlm.nih.gov/pubmed/35406479
http://dx.doi.org/10.3390/cancers14071707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996877/
https://www.ncbi.nlm.nih.gov/pubmed/35406479
http://dx.doi.org/10.3390/cancers14071707

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