Sphingosine 1-Phosphate Receptor 5 (S1P5) Deficiency Promotes Proliferation and Immortalization of Mouse Embryonic Fibroblasts

SIMPLE SUMMARY: Sphingosine 1-phosphate (S1P) is a lipid metabolite involved in cell proliferation, survival or migration. S1P is a ligand for five high-affinity G protein-coupled receptors (S1P1-5), which differ in their tissue distribution, and the specific effects of S1P depend on the suite of S1...

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Detalles Bibliográficos
Autores principales: Talmont, Franck, Mitri, Elodie, Dozier, Christine, Besson, Arnaud, Cuvillier, Olivier, Hatzoglou, Anastassia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996878/
https://www.ncbi.nlm.nih.gov/pubmed/35406433
http://dx.doi.org/10.3390/cancers14071661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996878/
https://www.ncbi.nlm.nih.gov/pubmed/35406433
http://dx.doi.org/10.3390/cancers14071661

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