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Sphingosine 1-Phosphate Receptor 5 (S1P5) Deficiency Promotes Proliferation and Immortalization of Mouse Embryonic Fibroblasts
SIMPLE SUMMARY: Sphingosine 1-phosphate (S1P) is a lipid metabolite involved in cell proliferation, survival or migration. S1P is a ligand for five high-affinity G protein-coupled receptors (S1P1-5), which differ in their tissue distribution, and the specific effects of S1P depend on the suite of S1...
Autores principales: | Talmont, Franck, Mitri, Elodie, Dozier, Christine, Besson, Arnaud, Cuvillier, Olivier, Hatzoglou, Anastassia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996878/ https://www.ncbi.nlm.nih.gov/pubmed/35406433 http://dx.doi.org/10.3390/cancers14071661 |
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