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Immunomodulatory Properties of Immune Checkpoint Inhibitors—More than Boosting T-Cell Responses?

SIMPLE SUMMARY: Tumor immune evasion is mediated in large part by the inhibition of anti-tumor T cell responses. Both the induction of tumor antigen-specific T cells and the activation state of T effector cells may be attenuated by surface receptors, which upon binding to counter receptors on immuno...

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Detalles Bibliográficos
Autores principales: Kuske, Michael, Haist, Maximilian, Jung, Thomas, Grabbe, Stephan, Bros, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996886/
https://www.ncbi.nlm.nih.gov/pubmed/35406483
http://dx.doi.org/10.3390/cancers14071710