Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet

SIMPLE SUMMARY: The nuclear protein Krüppel-like factor 9 (KLF9) suppresses development of cancers in multiple tissues including the liver. However, a mechanistic basis for how KLF9 decreases cancer initiation/development has not been elucidated. Here, we used a mouse model in which the Klf9 gene wa...

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Detalles Bibliográficos
Autores principales: Brown, Adam R., Alhallak, Iad, Simmen, Rosalia C. M., Melnyk, Stepan B., Heard-Lipsmeyer, Melissa E., Montales, Maria Theresa E., Habenicht, Daniel, Van, Trang T., Simmen, Frank A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996893/
https://www.ncbi.nlm.nih.gov/pubmed/35406507
http://dx.doi.org/10.3390/cancers14071737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996893/
https://www.ncbi.nlm.nih.gov/pubmed/35406507
http://dx.doi.org/10.3390/cancers14071737

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