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Reduction of Metastasis via Epigenetic Modulation in a Murine Model of Metastatic Triple Negative Breast Cancer (TNBC)

SIMPLE SUMMARY: We investigate the use of the small molecule epigenetic modulator 4SC-202 as a potential cancer therapeutic or adjuvant for Triple Negative Breast Cancer (TNBC). Epigenetic modulation involves alteration of the cellular phenotype without altering the genotype. Here, we investigate ho...

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Detalles Bibliográficos
Autores principales: Zylla, Jessica L. S., Hoffman, Mariah M., Plesselova, Simona, Bhattacharya, Somshuvra, Calar, Kristin, Afeworki, Yohannes, de la Puente, Pilar, Gnimpieba, Etienne Z., Miskimins, W. Keith, Messerli, Shanta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996906/
https://www.ncbi.nlm.nih.gov/pubmed/35406526
http://dx.doi.org/10.3390/cancers14071753