5-Azacytidine Downregulates the Proliferation and Migration of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Targeting miR-139-5p/ROCK2 Pathway

SIMPLE SUMMARY: For hepatocellular carcinoma (HCC), the second most common cause of cancer-related death, effective therapeutic approaches are lacking. As aberrant gene methylation is a major contributor to the development of HCC, demethylating drugs such as 5-azacytidine (5-Aza) have been proposed....

Descripción completa

Detalles Bibliográficos
Autores principales: Tonon, Federica, Cemazar, Maja, Kamensek, Urska, Zennaro, Cristina, Pozzato, Gabriele, Caserta, Sergio, Ascione, Flora, Grassi, Mario, Guido, Stefano, Ferrari, Cinzia, Cansolino, Laura, Trotta, Francesco, Kuzmanov, Biljana Grcar, Forte, Giancarlo, Martino, Fabiana, Perrone, Francesca, Bomben, Riccardo, Gattei, Valter, Elvassore, Nicola, Murano, Erminio, Truong, Nhung Hai, Olson, Michael, Farra, Rossella, Grassi, Gabriele, Dapas, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996928/
https://www.ncbi.nlm.nih.gov/pubmed/35406401
http://dx.doi.org/10.3390/cancers14071630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996928/
https://www.ncbi.nlm.nih.gov/pubmed/35406401
http://dx.doi.org/10.3390/cancers14071630

Ejemplares similares