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Evaluation of the TCR Repertoire as a Predictive and Prognostic Biomarker in Cancer: Diversity or Clonality?

SIMPLE SUMMARY: The TCR is the T cell antigen receptor, and it is responsible of the T cell activation, through the HLA-antigen complex recognition. Studying the TCR repertoire in patients with cancer can help to better understand the anti-tumoural responses and it has been suggested to have predict...

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Detalles Bibliográficos
Autores principales: Aran, Andrea, Garrigós, Laia, Curigliano, Giuseppe, Cortés, Javier, Martí, Mercè
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996954/
https://www.ncbi.nlm.nih.gov/pubmed/35406543
http://dx.doi.org/10.3390/cancers14071771