Converged DNA Damage Response Renders Human Hepatocellular Carcinoma Sensitive to CDK7 Inhibition

SIMPLE SUMMARY: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. HCC has a dismal five-year mortality estimate of >95%, ranking as the fourth leading cause of cancer-related mortality worldwide. Despite the recent progression in the treatment of HCC with multikinase...

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Detalles Bibliográficos
Autores principales: Xie, Guiqin, Zhu, Ailin, Gu, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996977/
https://www.ncbi.nlm.nih.gov/pubmed/35406486
http://dx.doi.org/10.3390/cancers14071714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996977/
https://www.ncbi.nlm.nih.gov/pubmed/35406486
http://dx.doi.org/10.3390/cancers14071714

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