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Converged DNA Damage Response Renders Human Hepatocellular Carcinoma Sensitive to CDK7 Inhibition
SIMPLE SUMMARY: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. HCC has a dismal five-year mortality estimate of >95%, ranking as the fourth leading cause of cancer-related mortality worldwide. Despite the recent progression in the treatment of HCC with multikinase...
Autores principales: | Xie, Guiqin, Zhu, Ailin, Gu, Xinbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996977/ https://www.ncbi.nlm.nih.gov/pubmed/35406486 http://dx.doi.org/10.3390/cancers14071714 |
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