E-Cadherin-Deficient Cells Are Sensitive to the Multikinase Inhibitor Dasatinib

SIMPLE SUMMARY: Inactivating mutations in the CDH1 gene, encoding the cell adhesion protein E-cadherin, cause hereditary diffuse gastric cancer syndrome (HDGC), as well as being a hallmark of sporadic diffuse gastric cancers and lobular breast cancers. We have previously identified AKT3 as a potenti...

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Detalles Bibliográficos
Autores principales: Bougen-Zhukov, Nicola, Decourtye-Espiard, Lyvianne, Mitchell, Wilson, Redpath, Kieran, Perkinson, Jacqui, Godwin, Tanis, Black, Michael A., Guilford, Parry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996982/
https://www.ncbi.nlm.nih.gov/pubmed/35406381
http://dx.doi.org/10.3390/cancers14071609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996982/
https://www.ncbi.nlm.nih.gov/pubmed/35406381
http://dx.doi.org/10.3390/cancers14071609

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