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miR-214-3p Is Commonly Downregulated by EWS-FLI1 and by CD99 and Its Restoration Limits Ewing Sarcoma Aggressiveness

SIMPLE SUMMARY: Ewing’s sarcoma (EWS), the second most frequent primary tumor of bone in the pediatric population, is a very aggressive, undifferentiated mesenchymal malignancy with a high tendency to develop lung and/or bone metastasis. The prognosis of patients with metastasis remains dismal, and...

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Detalles Bibliográficos
Autores principales: De Feo, Alessandra, Pazzaglia, Laura, Ciuffarin, Lisa, Mangiagli, Fabio, Pasello, Michela, Simonetti, Elisa, Pellegrini, Evelin, Ferrari, Cristina, Bianchi, Giuseppe, Spazzoli, Benedetta, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997046/
https://www.ncbi.nlm.nih.gov/pubmed/35406534
http://dx.doi.org/10.3390/cancers14071762