Cargando…
miR-214-3p Is Commonly Downregulated by EWS-FLI1 and by CD99 and Its Restoration Limits Ewing Sarcoma Aggressiveness
SIMPLE SUMMARY: Ewing’s sarcoma (EWS), the second most frequent primary tumor of bone in the pediatric population, is a very aggressive, undifferentiated mesenchymal malignancy with a high tendency to develop lung and/or bone metastasis. The prognosis of patients with metastasis remains dismal, and...
Autores principales: | De Feo, Alessandra, Pazzaglia, Laura, Ciuffarin, Lisa, Mangiagli, Fabio, Pasello, Michela, Simonetti, Elisa, Pellegrini, Evelin, Ferrari, Cristina, Bianchi, Giuseppe, Spazzoli, Benedetta, Scotlandi, Katia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997046/ https://www.ncbi.nlm.nih.gov/pubmed/35406534 http://dx.doi.org/10.3390/cancers14071762 |
Ejemplares similares
-
The role of FLI-1-EWS, a fusion gene reciprocal to EWS-FLI-1, in Ewing sarcoma
por: Elzi, David J., et al.
Publicado: (2015) -
Downstream EWS/FLI1 - upstream Ewing's sarcoma
por: Kovar, Heinrich
Publicado: (2010) -
Targeted Therapy for EWS-FLI1 in Ewing Sarcoma
por: Gong, Helong, et al.
Publicado: (2023) -
CD99 at the crossroads of physiology and pathology
por: Pasello, Michela, et al.
Publicado: (2018) -
Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma
por: Herrero-Martin, David, et al.
Publicado: (2011)